PRAYAS Punjab - Apni Zubaan Mein

We are thrilled to announce our online/offline conversation series titled "Apni Zuban Mein". The initial interaction will be arranged from January 22 and the subsequent interactions will be twice a month (bi-monthly).

t will be an interactive show, and it will be presented entirely in Hindi. We wanted to make the talk understandable to a general audience, so we decided that the speech should be as straight as possible. The presentation will begin with a historical context of the study, which can then be gradually linked to the speaker's ongoing research and applications.

We anticipate that many students will be able to learn, understand, and gain the knowledge and experience of a speaker with complex research.

Abstract

Nearly one in twenty people worldwide suffer from neurological diseases. Early detection is crucial for these diseases because timely intervention can halt the progression of the condition and stop it from worsening. Early detection, however, relies on ultrasensitive biomarker detection, which is not possible with conventional diagnostic techniques. Neurodegenerative diseases can be detected by the presence or elevated levels of specific biomarkers in blood. The ability to identify single molecules reliably, swiftly, quantitatively, and affordably would thus offer up exciting new opportunities for a variety of biomedical applications.

We are investigating a unique nanopore-based sensing platform allowing reliable and highly sensitive detection and identification of different biomolecules in complex solutions. This platform employs scalable and controllable methods to fabricate silicon nitride membranes with effective thickness down to ~1.5 nm. Ultra-stable nanopores exhibiting high lifetime are fabricated in these membranes using controlled breakdown technique and track-etch technology. By adjusting the membrane composition as well as the nanopore structure, the translocation kinetics of the biomolecules can be tailored. Using this platform, we have demonstrated the detection of a number of isolated analytes, including DNA, proteins, and antibodies. We combine the novel nanopore sensor with artificial intelligence-based single-molecule identification algorithms with an aim to use the platform for the early diagnosis of neurodegenerative disorders. Artificial intelligence and on-the-fly data processing integrated with our novel nanopore platform may allow for the precise identification and measurement of the many biomarkers present in blood serum as well as ‘real-time’ diagnosis of Alzheimer's and Multiple Sclerosis.

Abstract

Nearly one in twenty people worldwide suffer from neurological diseases. Early detection is crucial for these diseases because timely intervention can halt the progression of the condition and stop it from worsening. Early detection, however, relies on ultrasensitive biomarker detection, which is not possible with conventional diagnostic techniques. Neurodegenerative diseases can be detected by the presence or elevated levels of specific biomarkers in blood. The ability to identify single molecules reliably, swiftly, quantitatively, and affordably would thus offer up exciting new opportunities for a variety of biomedical applications.

We are investigating a unique nanopore-based sensing platform allowing reliable and highly sensitive detection and identification of different biomolecules in complex solutions. This platform employs scalable and controllable methods to fabricate silicon nitride membranes with effective thickness down to ~1.5 nm. Ultra-stable nanopores exhibiting high lifetime are fabricated in these membranes using controlled breakdown technique and track-etch technology. By adjusting the membrane composition as well as the nanopore structure, the translocation kinetics of the biomolecules can be tailored. Using this platform, we have demonstrated the detection of a number of isolated analytes, including DNA, proteins, and antibodies. We combine the novel nanopore sensor with artificial intelligence-based single-molecule identification algorithms with an aim to use the platform for the early diagnosis of neurodegenerative disorders. Artificial intelligence and on-the-fly data processing integrated with our novel nanopore platform may allow for the precise identification and measurement of the many biomarkers present in blood serum as well as ‘real-time’ diagnosis of Alzheimer's and Multiple Sclerosis.

Abstract

I will be talking about the evolution of our universe just after the big-bang explosion to the current time. This will be a very naive interactive session from the particle physics and cosmological prospective.

Abstract

1. Discussion on role of Creativity and Innovation in world of AI and ML.

2. How to future proof your career.

2. Design your product/service from scratch to prototype.